Protein carbonyl levels in serum and gingival crevicular fluid in patients with chronic periodontitis

BALTACIOĞLU E., AKALIN F. A., ALVER A., DEĞER O., KARABULUT E.

ARCHIVES OF ORAL BIOLOGY, vol.53, no.8, pp.716-722, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 53 Issue: 8
  • Publication Date: 2008
  • Doi Number: 10.1016/j.archoralbio.2008.02.002
  • Journal Name: ARCHIVES OF ORAL BIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.716-722
  • Keywords: protein oxidation, protein carbonyls, oxidative stress, periodontitis, gingival crevicular fluid, TOTAL ANTIOXIDANT CAPACITY, OXIDATIVELY MODIFIED PROTEINS, LIPID-PEROXIDATION, REACTIVE OXYGEN, POSTMENOPAUSAL WOMEN, FREE-RADICALS, DISEASE, SALIVA, TISSUE, INFLAMMATION
  • Karadeniz Technical University Affiliated: Yes

Abstract

Objective: Evidence reveals the role of reactive oxygen species (ROS) in many pathologies including periodontitis. Protein carbanylation is the most widely used biomarker for oxidative damage to proteins, and reflects cellular damage induced by ROS. In this study protein carbonyl (PC) levels in serum and gingival crevicular fluid (GCF) in patients with chronic periodontitis (CP) was evaluated.