Clinicopathologic characteristics and BRCA-1/BRCA-2 mutations of Turkish patients with breast cancer

AYDIN F., AKAGUN T., YILDIZ B., FIDAN E., OZDEMIR F., Kavgaci H.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.112, sa.9, ss.521-523, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 112 Sayı: 9
  • Basım Tarihi: 2011
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.521-523
  • Anahtar Kelimeler: BRCA-1, BRCA-2, breast cancer, LARGE GENOMIC REARRANGEMENTS, BRCA1 GENE, IDENTIFICATION, DELETIONS
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Background: BRCA-1 and BRCA-2 are two major susceptibility genes for breast cancer. Between 30-70 %. of hereditary breast cancers are thought to be attributed to mutations in BRCA-1 or BRCA-2. The aim of our study was to investigate the clinicopathologic characteristics and BRCA mutations of patients with breast cancer living in the northeast region of Turkey.