The effects of topiramate and valproate therapy on insulin, c-peptide, leptin, neuropeptide Y, adiponectin, visfatin, and resistin levels in children with epilepsy

Sonmez, Fatma; Zaman, Dilek; AKSOY, Ayse; DEĞER, ORHAN; ALİYAZICIOĞLU, REZZAN; KARAGÜZEL, GÜLAY; FAZLIOGLU, Kerim

doi:10.1016/j.seizure.2013.07.007

The effects of topiramate and valproate therapy on insulin, c-peptide, leptin, neuropeptide Y, adiponectin, visfatin, and resistin levels in children with epilepsy

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Sonmez F. M., Zaman D., AKSOY A., DEĞER O., ALİYAZICIOĞLU R., KARAGÜZEL G., ...More

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, vol.22, no.10, pp.856-861, 2013 (SCI-Expanded)

Publication Type: Article / Article
Volume: 22 Issue: 10
Publication Date: 2013
Doi Number: 10.1016/j.seizure.2013.07.007
Journal Name: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.856-861
Keywords: Valproate, Topiramate, Weight, Adipocytokines, Insulin, C-peptide, WEIGHT-GAIN, BODY-COMPOSITION, SERUM-INSULIN, GLUCOSE, OBESITY, WOMEN, PREDICTORS, METABOLISM, SECRETION, ENERGY
Karadeniz Technical University Affiliated: Yes

Abstract

Purpose: Antiepileptic drugs may affect the endocrine system. We investigated the effects of valproic acid and topiramate on the levels of insulin, c-peptide and adipocytokines in pre-pubertal patients with idiopathic partial and generalized epilepsy.