The effects of topiramate and valproate therapy on insulin, c-peptide, leptin, neuropeptide Y, adiponectin, visfatin, and resistin levels in children with epilepsy

Sonmez, Fatma; Zaman, Dilek; AKSOY, Ayse; DEĞER, ORHAN; ALİYAZICIOĞLU, REZZAN; KARAGÜZEL, GÜLAY; FAZLIOGLU, Kerim

doi:10.1016/j.seizure.2013.07.007

The effects of topiramate and valproate therapy on insulin, c-peptide, leptin, neuropeptide Y, adiponectin, visfatin, and resistin levels in children with epilepsy

Sonmez F. M., Zaman D., AKSOY A., DEĞER O., ALİYAZICIOĞLU R., KARAGÜZEL G., ...Daha Fazla

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, cilt.22, sa.10, ss.856-861, 2013 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 22 Sayı: 10
Basım Tarihi: 2013
Doi Numarası: 10.1016/j.seizure.2013.07.007
Dergi Adı: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.856-861
Anahtar Kelimeler: Valproate, Topiramate, Weight, Adipocytokines, Insulin, C-peptide, WEIGHT-GAIN, BODY-COMPOSITION, SERUM-INSULIN, GLUCOSE, OBESITY, WOMEN, PREDICTORS, METABOLISM, SECRETION, ENERGY
Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Purpose: Antiepileptic drugs may affect the endocrine system. We investigated the effects of valproic acid and topiramate on the levels of insulin, c-peptide and adipocytokines in pre-pubertal patients with idiopathic partial and generalized epilepsy.