Open greenways play significant roles for city residents, urban climate, and urban ecosystems. Open green spaces are a combination of systems providing ecological, aesthetic, economic, and recreational benefits. Due to new technologies, rapid increases of population, industrialization, and irregular urbanization, open and green spaces in urban areas are decreasing. Open green spaces in urban areas improve the quality of life of city residents and bring out social and cultural characteristics of a city. In this study, the city of Amasya, Turkey was selected as the study area largely due to its natural, historical, tourist, and traditional values. Amasya is located next to Yesilrmak River and Valley, and it is known for its historical-cultural texture. The purpose of the current study is to design a multifunctional greenway system that will protect the natural, historical, and cultural values of Amasya city, passing through important focal points for the city, and ensuring sustainability by supporting Yeilrmak Valley. In this respect, important focal points were determined for the city. A survey was conducted among 105 people to determine focal points that are important for recreational opportunities, and expectations and preferences of residents of Amasya. Optimum greenway routes were also determined using network analysis in a geographical information system environment with current development plans and greenway planning criteria. Finally, the following routes were identified: (1)Amasya-Erzincan Road Corridor, (2)Yeilrmak River Corridor, and (3)Amasya Castle Corridor. Respective maps were created for these corridors.