Efficient Synthesis of Benzimidazoles Containing 1,2,4-Triazol-3-One Nucleus Using Microwave Technique

Mentese E., KAHVECİ B.

CHEMISTRY OF HETEROCYCLIC COMPOUNDS, cilt.52, sa.11, ss.948-951, 2016 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 52 Sayı: 11
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1007/s10593-017-1991-2
  • Dergi Adı: CHEMISTRY OF HETEROCYCLIC COMPOUNDS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.948-951
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

A series of new compounds containing both benzimidazole and 1,2,4-triazol-3-one rings was synthesized by microwave irradiation of mixtures containing 5-(alkyl/phenyl)-4-(4-carboxyphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-ones and 1,2-diaminobenzene derivatives. Also, benzimidazole derivatives were synthesized by the reaction of ethyl 2-(ethoxy(alkyl/phenyl)methylene)hydrazine-1-carboxylates with 2-aminobenzimidazole. A rapid and efficient combination of 1,2,4-triazol-3-one and benzimidazole ring systems was achieved for the first time in this study.