The ratio of second- and fourth-digit lengths and congenital adrenal hyperplasia due to 21-hydroxylase deficiency


Okten A. N. , Kalyoncu M. , Yaris N.

EARLY HUMAN DEVELOPMENT, cilt.70, ss.47-54, 2002 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 70
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1016/s0378-3782(02)00073-7
  • Dergi Adı: EARLY HUMAN DEVELOPMENT
  • Sayfa Sayıları: ss.47-54

Özet

Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency results in excessive androgen exposure in the gestational period and various degrees of masculinization of the external genitalia in female foetuses. Intrauterine gonadal steroids are not only essential for the development of the genital organs but also affect some other extragenital organ development.