A convenient synthesis of some 3-alkylamino-4,5-dihydro-1H-1,2,4-triazol-5-ones
REVUE ROUMAINE DE CHIMIE, cilt.48, sa.8, ss.615-618, 2003 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 48 Sayı: 8
- Basım Tarihi: 2003
- Dergi Adı: REVUE ROUMAINE DE CHIMIE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.615-618
- Karadeniz Teknik Üniversitesi Adresli: Evet
Özet
A series of 3-arylidenamino-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-5-ones N were obtained from the reaction of 3-amino-4-phenyl-45-dihydro-1H-1,2,4-triazol-5-one IVa with certain aldehydes. Compounds V were hydrogenated with NaBH, in diglyme to afford 3-alkylamino-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-5-ones. VI. So, a general and convenient method was improved for the synthesis of type VI compounds. Eleven new and potential biologically active compounds were synthesized and characterized by elemental analyses, C-13-NMR, H-1-NMR, UV and IR spectra.