Frequency of cardiovascular and gastrointestinal malformations, leukemia and hypothyroidism in children with Down syndrome in Trabzon, Turkey
TURKISH JOURNAL OF PEDIATRICS, vol.40, no.1, pp.103-109, 1998 (SCI-Expanded, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 40 Issue: 1
- Publication Date: 1998
- Journal Name: TURKISH JOURNAL OF PEDIATRICS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Page Numbers: pp.103-109
- Karadeniz Technical University Affiliated: Yes
Abstract
This study was carried out to determine the frequency of congenital heart defects, cholelithiasis, hypothyroidism and leukemia in 31 children with Down syndrome. Twenty children (71.4%) had congenital heart defects. Ultrasonography was performed on 29 and two of these (6.9%) had cholelithiasis. Tests for hypothyroidism in 24 children identified hypothyroidism in three (12.5%). Leukemia was diagnosed in three children (10%).(one with congenital, two acquired). One patient with congenital hypothyroidism underwent surgery on the third day of life because of annular pancreas and duodenal atresia.