Blood levels of cytokines in children with idiopathic partial and generalized epilepsy

Creative Commons License

Sonmez F. M., Serin H. M., ALVER A., ALİYAZICIOĞLU R., CANSU A., Cane G., ...Daha Fazla

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, cilt.22, sa.7, ss.517-521, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 7
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.seizure.2013.03.014
  • Dergi Adı: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.517-521
  • Anahtar Kelimeler: ILs, TNF-alpha, Topiramate, Valproic acid, Epilepsy, Child, ANTIEPILEPTIC DRUGS, TNF-ALPHA, IMMUNOGLOBULIN LEVELS, STATUS EPILEPTICUS, PLASMA-LEVELS, SEIZURES, SYSTEM, INTERLEUKIN-6, IMMUNOREACTIVITY, INFLAMMATION
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Purpose: Antiepileptic drugs have been reported to reduce the levels of serum immunoglobulins and affect the production and levels of certain cytokines. We investigated the effects of valproic acid (VPA) and topiramate (TPM) on the blood levels of interleukin (IL)-alpha, IL-1 beta, IL-6, IL-10, and TNF-alpha in children with idiopathic generalized and partial epilepsy.