Analgesic effects of mad honey (grayanotoxin) in mice models of acute pain and painful diabetic neuropathy


GÜNDÜZ A., Eraydin I., Turkmen S., KALKAN Ö. F., TÜREDİ S., Eryigit U., ...More

HUMAN & EXPERIMENTAL TOXICOLOGY, vol.33, no.2, pp.130-135, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 2
  • Publication Date: 2014
  • Doi Number: 10.1177/0960327113482693
  • Journal Name: HUMAN & EXPERIMENTAL TOXICOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.130-135
  • Keywords: Mad honey, grayanotoxin, pain, diabetic neuropathy, mice, streptozotocin, SODIUM-CHANNELS, STREPTOZOTOCIN, NOCICEPTION
  • Karadeniz Technical University Affiliated: Yes

Abstract

Objectives: The aim of this experimental study was to investigate the effects of mad honey (grayanotoxin, GTX), used in complementary medicine for a variety of purposes besides being food, on pain thresholds in normal mice as model for acute pain and diabetic mouse as model for neuropathic pain.