Evaluation of the Post-Mortem Superoxide Dismutase, Glutathione Peroxidase Activities and Malondialdehyde Level in Renal and Brain Tissues: Is it Possible to Estimate Post-Mortem Interval Using these Parameters?


Gumus B., Gumus A., YILDIRIM A., ÖZER E., Ozyurt H., Sahin M., ...More

CLINICAL LABORATORY, vol.61, no.9, pp.1205-1211, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 61 Issue: 9
  • Publication Date: 2015
  • Doi Number: 10.7754/clin.lab.2015.150213
  • Journal Name: CLINICAL LABORATORY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1205-1211
  • Keywords: postmortem interval (PMI), thanatochemistry, superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), malondialdehyde (MDA), TEMPERATURE, HYPOXIA, ASSAY
  • Karadeniz Technical University Affiliated: Yes

Abstract

Background: Estimation of the postmortem interval (PM!) is one major area of interest in forensic medicine. We investigated changes of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities and malondialdehyde (MDA) levels in rat brain and renal tissues in the PMI and examined the potential changes which may be useful for an estimation of time of death.