JOURNAL OF BACK AND MUSCULOSKELETAL REHABILITATION, vol.20, pp.123-125, 2007 (SCI-Expanded)
Ankylosing spondylitis (AS) is a systemic, chronic and inflammatory disease of uncertain etiology particularly affecting the spine and sacroiliac joints. At present, biological agents are used in cases resistant to treatment. However, there are safety problems regarding the use of these agents in patients with chronic viral hepatitis. We report a case monitored with a diagnosis of AS whose inactive HBV (hepatitis B virus) carrier state improved with antitumor necrosis factor-alpha (anti-TNF) treatment (infliximab).