Erythema dyschromicum perstans: Response to dapsone therapy

BAHADIR S., Cobanoglu U. , CIMSIT G. , YAYLI S. , ALPAY K.

INTERNATIONAL JOURNAL OF DERMATOLOGY, cilt.43, ss.220-222, 2004 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 43 Konu: 3
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1111/j.1365-4632.2004.01984.x
  • Sayfa Sayıları: ss.220-222


Erythema dyschromicum perstans (EDP) is a rare disorder characterized by asymptomatic, slowly progressive, ash-gray macular pigmentation of the skin, which usually occurs from age 5 years through adult life. Most cases reported to date are of Latin American and Indian patients. Rare cases has been reported from Turkey. No treatment of choice is presently available. Various therapies have been tried, including sun protection, chemical peels, antibiotics, corticosteroids, vitamins, isoniazid, griseofulvin, and chloroquine, without any benefit. Some authors have suggested the therapeutic efficacy of clofazimine and dapsone on EDP. We report a case of EDP that responded remarkably well to treatment with dapsone.