Prevalence of integrons and a new dfrA17 variant in Gram-negative bacilli which cause community-acquired infections
MICROBIOLOGY AND IMMUNOLOGY, vol.54, no.3, pp.164-169, 2010 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 54 Issue: 3
- Publication Date: 2010
- Doi Number: 10.1111/j.1348-0421.2010.00197.x
- Journal Name: MICROBIOLOGY AND IMMUNOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.164-169
- Keywords: community-acquired infections, Gram-negative bacilli, integrons, UROPATHOGENIC ESCHERICHIA-COLI, INTENSIVE-CARE-UNIT, ANTIBIOTIC-RESISTANCE, GENE CASSETTES, PSEUDOMONAS-AERUGINOSA, MOLECULAR EPIDEMIOLOGY, TURKEY, ENTEROBACTERIACEAE, PATTERNS, CLASS-1
- Karadeniz Technical University Affiliated: Yes
Abstract
A hundred and eleven Gram-negative bacilli from community-acquired infections were characterized by antimicrobial susceptibility testing, screened for class 1 and 2 integrons, and statistically evaluated for the association between antibiotic profile and the presence of integrons. The frequency with which integrons were harbored was 28.8%. Three E. coli strains contained a dfrA17 variant inserted in a class 1 integron. Results of PFGE indicated that some E. coli strains carrying integrons were clonally related. Carriage of gene cassettes was significantly associated with resistance to certain antibiotics (P < 0.05).