Prevalence of integrons and a new dfrA17 variant in Gram-negative bacilli which cause community-acquired infections


Sandalli C., BURUK C. K., SANCAKTAR M., ÖZGÜMÜŞ O. B.

MICROBIOLOGY AND IMMUNOLOGY, cilt.54, sa.3, ss.164-169, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 54 Sayı: 3
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1111/j.1348-0421.2010.00197.x
  • Dergi Adı: MICROBIOLOGY AND IMMUNOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.164-169
  • Anahtar Kelimeler: community-acquired infections, Gram-negative bacilli, integrons, UROPATHOGENIC ESCHERICHIA-COLI, INTENSIVE-CARE-UNIT, ANTIBIOTIC-RESISTANCE, GENE CASSETTES, PSEUDOMONAS-AERUGINOSA, MOLECULAR EPIDEMIOLOGY, TURKEY, ENTEROBACTERIACEAE, PATTERNS, CLASS-1
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

A hundred and eleven Gram-negative bacilli from community-acquired infections were characterized by antimicrobial susceptibility testing, screened for class 1 and 2 integrons, and statistically evaluated for the association between antibiotic profile and the presence of integrons. The frequency with which integrons were harbored was 28.8%. Three E. coli strains contained a dfrA17 variant inserted in a class 1 integron. Results of PFGE indicated that some E. coli strains carrying integrons were clonally related. Carriage of gene cassettes was significantly associated with resistance to certain antibiotics (P < 0.05).