The effects of melatonin on human hepatoma (Hep G2) cell line.


ÖZDEMİR F. , DENİZ O., KAYNAR K., ARSLAN M., Kavgaci H. , YILDIZ B., ...More

Bratislavske lekarske listy, vol.110, no.5, pp.276-9, 2009 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 110 Issue: 5
  • Publication Date: 2009
  • Title of Journal : Bratislavske lekarske listy
  • Page Numbers: pp.276-9
  • Keywords: melatonin, hepatoma, cell line, Hep G2, BREAST-CANCER CELLS, GROWTH IN-VIVO, POSSIBLE INVOLVEMENT, APOPTOSIS, PROLIFERATION, INHIBITION, RECEPTOR, CYCLE, EXPRESSION, THERAPY

Abstract

Background. Melatonin has been suggested to have antiproliferative effects on cancer cells. These effects can be attributed to immunomodulation, growth factor inhibition, induction of apoptosis and prooxidant properties. Melatonin is considered as a safe drug with minimal adverse effects.