Amlodipine-Associated Liver Injury: Disentangling Causality in Perioperative Polypharmacy


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ANNALS OF PHARMACOTHERAPY, cilt.0, sa.0, ss.1-3, 2026 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Editöre Mektup
  • Cilt numarası: 0 Sayı: 0
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1177/10600280261504054
  • Dergi Adı: ANNALS OF PHARMACOTHERAPY
  • Derginin Tarandığı İndeksler: Scopus, Science Citation Index Expanded (SCI-EXPANDED), BIOSIS, CINAHL, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.1-3
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

A letter describing mixed-pattern liver injury after perioperative initiation of a perindopril/amlodipine fixed-dose combination. Several potentially hepatotoxic drugs were started together after robotic radical prostatectomy; a structured, liver-specific causality assessment (RUCAM, Naranjo), comparison of each drug's typical injury pattern, and a selective dechallenge identified amlodipine as the likely cause.