© AEPress s.r.o.OBJECTIVE: This preliminary study aims to examine a change in the blood levels of irisin in patients with acute pericarditis (AP) and acute myopericarditis (AMP) and examine the diagnostic value of the serum irisin level in AP and AMP. METHODS: 10 patients, who applied to the emergency service and cardiology clinic with chest pain and who were diagnosed with AP and 5 patients, who were diagnosed with AMP as a result of routine examinations, were included in the study. The basal laboratory parameters, echocardiography fi ndings and serum irisin levels of the patients and during check one month later were examined. RESULTS: While the basal irisin levels were found to be signifi cantly low in the AMP group and high during the check (6.6 ± 1.58, 8.19 ± 1.43, respectively), no statistically signifi cant difference was determined (p = 0.23). It was observed that the basal and control irisin levels did not vary signifi cantly in the AP group (8.03 ± 1.6, 8.19 ± 1.43, respectively) (p = 0.84). CONCLUSION: In this preliminary study, the basal irisin levels were found to be signifi cantly low in the AMP group, while there was no statistically signifi cant difference between the basal irisin levels and control irisin levels in the AP and AMP groups.