Neuronal Nitric Oxide Signaling Regulates Erection Recovery After Cavernous Nerve Injury

Sezen S. F., Lagoda G., Burnett A. L.

JOURNAL OF UROLOGY, cilt.187, sa.2, ss.757-763, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 187 Sayı: 2
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.juro.2011.09.146
  • Dergi Adı: JOURNAL OF UROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.757-763
  • Anahtar Kelimeler: penis, nitric oxide synthase type I, erectile dysfunction, apoptosis, prostatectomy, SPINAL-CORD, SYNTHASE, DYSFUNCTION, MICE, INHIBITION, PROSTATECTOMY, SILDENAFIL, MODEL, FK506, REGENERATION
  • Karadeniz Teknik Üniversitesi Adresli: Hayır

Özet

Purpose: Nitric oxide is the major neuronal mediator of penile erection but its role in erectile function status after cavernous nerve injury is uncertain. We determined the function of neuronal nitric oxide signaling in the pathobiology of erectile function recovery after partial cavernous nerve injury using genetic and pharmacological mouse experimental paradigms.