Neuronal Nitric Oxide Signaling Regulates Erection Recovery After Cavernous Nerve Injury
JOURNAL OF UROLOGY, vol.187, no.2, pp.757-763, 2012 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 187 Issue: 2
- Publication Date: 2012
- Doi Number: 10.1016/j.juro.2011.09.146
- Journal Name: JOURNAL OF UROLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.757-763
- Keywords: penis, nitric oxide synthase type I, erectile dysfunction, apoptosis, prostatectomy, SPINAL-CORD, SYNTHASE, DYSFUNCTION, MICE, INHIBITION, PROSTATECTOMY, SILDENAFIL, MODEL, FK506, REGENERATION
- Karadeniz Technical University Affiliated: No
Abstract
Purpose: Nitric oxide is the major neuronal mediator of penile erection but its role in erectile function status after cavernous nerve injury is uncertain. We determined the function of neuronal nitric oxide signaling in the pathobiology of erectile function recovery after partial cavernous nerve injury using genetic and pharmacological mouse experimental paradigms.