Investigation of antioxidant, antityrosinase, and photoprotective activities of Eryngium billardieri with phytochemical profile


Subaş T., Badem M., Kanbolat Ş., Yılmaz M. A., Çakır O., Saylam N., ...Daha Fazla

IV Bio.Natural 2025 – Bioactive Natural Products Research Conference, Lisbon, Portekiz, 14 - 15 Temmuz 2025, ss.136, (Özet Bildiri)

  • Yayın Türü: Bildiri / Özet Bildiri
  • Basıldığı Şehir: Lisbon
  • Basıldığı Ülke: Portekiz
  • Sayfa Sayıları: ss.136
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Eryngium species are commonly used for the treatment of skin diseases and inflammation, as well as wound healing in folk medicine. It has been revealed that Eryngium sp. rich in compounds such as triterpene saponins, phenolic acids, flavonoids, and steroids show antioxidant, antimicrobial and anti-inflammatory activity. The aim of this study was to investigate the antioxidant, antityrosinase and photoprotective potential of the ethanol extracts prepared from the aerial parts of E. billardieri F.Delaroche using maceration and ultrasonic-assisted microwave extraction methods. Antioxidant capacity was determined by ferric reducing antioxidant power (FRAP), cupric ion reducing antioxidant capacity (CUPRAC) and 1,1-Diphenyl-2-picrylhydrazyl radical (DPPH) assays and photoprotective activity by in vitro sun protection factor (SPF) determination. The phytochemical profile of the more active extract was then determined using a validated LC-MS/MS method. According to the activity results, the ethanol extract obtained by ultrasonic-assisted microwave extraction was found to be more active in all experiments. LC-MS/MS analysis of this extract confirmed the presence of 28 compounds including isoquercitrin, quercitrin, rosmarinic acid, hesperidin, nicotiflorin, astragalin. Although further studies are needed, it is concluded that the extract of E. billardieri prepared using ultrasonic-assisted microwave extraction has significant potential as a cosmetic product ingredient.