Medical ozone therapy reduces oxidative stress and testicular damage in an experimental model of testicular torsion in rats

Tusat M., MENTEŞE A., DEMİR S., ALVER A., İMAMOĞLU M.

INTERNATIONAL BRAZ J UROL, cilt.43, sa.6, ss.1160-1166, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 6
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1590/s1677-5538.ibju.2016.0546
  • Dergi Adı: INTERNATIONAL BRAZ J UROL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1160-1166
  • Anahtar Kelimeler: Ischemia, Oxidative Stress, Spermatic Cord Torsion, ISCHEMIA-REPERFUSION INJURY, ISCHEMIA/REPERFUSION INJURY, N-ACETYLCYSTEINE, APOPTOSIS, ALBUMIN
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Objective: Testicular torsion (TT) refers to rotation of the testis and twisting of the spermatic cord. TT results in ischemia-reperfusion (I/R) injury involving increased oxidative stress, inflammation and apoptosis, and can even lead to infertility. The aim of this study was to investigate the effect of ozone therapy on testicular damage due to I/R injury in an experimental torsion model.