Intramolecular 4 pi photocyclization of chalconoid-like compounds in solution and antimicrobial activities


YAYLI N. , SIVRIKAYA S., YASAR A. , UCUNCU O., GULEC C., KOLAYLI S. , ...Daha Fazla

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, cilt.175, ss.22-28, 2005 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 175 Konu: 1
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1016/j.jphotochem.2005.03.025
  • Dergi Adı: JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
  • Sayfa Sayıları: ss.22-28

Özet

Two new (2 and 8) and eight known (1, 3-7, 9 and 10) o-, m-, p-nitro, -methoxy and -methyl substituted chalconoid and alnustone-like compounds with a skeleton of (2E,4E)-1,5-diarylpenta-2,4-dien- l -one (1-10) were synthesized and their 4n(pi) photocyclization reaction gave 10 new o-, m-, p-nitro, -methoxy and -methyl substituted cis-3-benzoyl-4-phenylcyclobutenes (11-20), stereoselectively, as major products in solution. The antimicrobial activities of all the compounds were also investigated. They showed antibacterial activity against Gram-positive bacteria, moderate antibacterial activity against Gram-negative bacteria, but no antifungal activity was observed against yeast-like fungi. (c) 2005 Elsevier B.V. All rights reserved.