Is Hyperbaric Oxygen Therapy Effective in Cisplatin-Induced Ototoxicity in Rats?

YALDIZ ÇOBANOĞLU, HATİCE; Vuralkan, Erkan; ARSLAN, ABDULLAH; Mirasoglu, Bengusu; Toklu, A.

doi:10.21053/ceo.2017.01704

Is Hyperbaric Oxygen Therapy Effective in Cisplatin-Induced Ototoxicity in Rats?

YALDIZ ÇOBANOĞLU H. B., Vuralkan E., ARSLAN A., Mirasoglu B., Toklu A. S.

CLINICAL AND EXPERIMENTAL OTORHINOLARYNGOLOGY, cilt.12, sa.1, ss.66-71, 2019 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 12 Sayı: 1
Basım Tarihi: 2019
Doi Numarası: 10.21053/ceo.2017.01704
Dergi Adı: CLINICAL AND EXPERIMENTAL OTORHINOLARYNGOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.66-71
Anahtar Kelimeler: Hyperbaric Oxygen, Cisplatin, Ototoxicity, Rats
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Objectives. Cisplatin is an antineoplastic agent, used in the treatment of different types of malignant neoplasms. Side effects such as ototoxicity, nephrotoxicity, and bone marrow toxicity are the main limitations of its clinical use. The aim of the present study was to evaluate the possible effects of hyperbaric oxygen (HBO) therapy as a protective agent in cisplatin-induced ototoxicity in rats.