CLINICAL AND EXPERIMENTAL OTORHINOLARYNGOLOGY, vol.12, no.1, pp.66-71, 2019 (SCI-Expanded)
Article / Article
CLINICAL AND EXPERIMENTAL OTORHINOLARYNGOLOGY
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Hyperbaric Oxygen, Cisplatin, Ototoxicity, Rats
Karadeniz Technical University Affiliated:
Objectives. Cisplatin is an antineoplastic agent, used in the treatment of different types of malignant neoplasms. Side effects such as ototoxicity, nephrotoxicity, and bone marrow toxicity are the main limitations of its clinical use. The aim of the present study was to evaluate the possible effects of hyperbaric oxygen (HBO) therapy as a protective agent in cisplatin-induced ototoxicity in rats.