Paraneoplastic Peripheral Neuropathy Preceding the Diagnosis of Hodgkin's Lymphoma: Differential Diagnosis


Kavgaci H. , SÖNMEZ M. , Cobanoglu U. , ALİOĞLU Z. , YILDIZ B., ÖZDEMİR F. , ...More

TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, vol.29, no.5, pp.1342-1345, 2009 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 5
  • Publication Date: 2009
  • Title of Journal : TURKIYE KLINIKLERI TIP BILIMLERI DERGISI
  • Page Numbers: pp.1342-1345

Abstract

A 30-year-old male patient presented with symptoms of peripheral neuropathy (PN). A work-up at that time failed to reveal an underlying disease. The patient received gabapentin for two months with no improvement and intravenous immunoglobulin (IVIG) was initiated subsequently. After sixteen months of IVIG therapy, lymphadenopathy and splenomegaly were detected. Diagnosis was Hodgkin's lymphoma (HL). Complete remission was observed with systemic polychemotherapy; however, HL relapsed one year later. High dose chemotherapy with autologous stem cell transplantation was performed and complete remission of HL was achieved during which PN also improved. Patients with unexplained PN should be evaluated for the presence of HL.