A convenient synthesis of some 4-(alkylamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones

Kahveci B., İkizler A.

TURKISH JOURNAL OF CHEMISTRY, cilt.24, sa.4, ss.343-351, 2000 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 4
  • Basım Tarihi: 2000
  • Dergi Adı: TURKISH JOURNAL OF CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.343-351
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

A series of 3-alkyl-4- (arylidenamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones, 6-10, was obtained from the reaction of the corresponding 3-alkyl-4-amino-4,5-dihydro-1H- 1,2,4-triazol-5-ones, 1, with the appropriate aldehydes. 3-alkyl-4-(alkylamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones of type 11-16 were synthesized from the selective reduction of compounds 5-10 with NaBH4 in diglyme or DMSO medium as a general and convenient method.