A convenient synthesis of some 4-(alkylamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones

Kahveci B., İkizler A.

TURKISH JOURNAL OF CHEMISTRY, vol.24, no.4, pp.343-351, 2000 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 4
  • Publication Date: 2000
  • Journal Name: TURKISH JOURNAL OF CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.343-351
  • Karadeniz Technical University Affiliated: Yes

Abstract

A series of 3-alkyl-4- (arylidenamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones, 6-10, was obtained from the reaction of the corresponding 3-alkyl-4-amino-4,5-dihydro-1H- 1,2,4-triazol-5-ones, 1, with the appropriate aldehydes. 3-alkyl-4-(alkylamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones of type 11-16 were synthesized from the selective reduction of compounds 5-10 with NaBH4 in diglyme or DMSO medium as a general and convenient method.