A case of osteogenesis imperfecta presenting with psychotic symptoms


ÖZKORUMAK KARAGÜZEL E. , SAĞLAM AYKUT D. , KIZILAY ÇANKAYA P., Karkucak M.

ANADOLU PSIKIYATRI DERGISI-ANATOLIAN JOURNAL OF PSYCHIATRY, vol.18, pp.23-25, 2017 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 18
  • Publication Date: 2017
  • Doi Number: 10.5455/apd.248586
  • Title of Journal : ANADOLU PSIKIYATRI DERGISI-ANATOLIAN JOURNAL OF PSYCHIATRY
  • Page Numbers: pp.23-25

Abstract

Objective: Osteogenesis imperfecta (OI) is regarded as a heterogeneous clinical condition. Genetic complexity and extensive phenotypic variation lead to heterogeneous clinical manifestations in the condition. Methods: A 33-year old, male underwent consultation because of irritability, reference ideas and aggressive behavior. Results: OI type-IV was diagnosed on the basis of physical examinations and radiological findings. Psychotic symptoms improved following low-dose antipsychotic treatment. Discussion: This report presents a rare case of OI with psychotic symptoms. Comorbidity of a psychiatric disorder and OI in a case with a positive family history for both may also emphasize a common genetic basis between the psychotic disorders and OI.