Correlation of Antenatal and Postnatal Maternal Uterine and Renal Artery Doppler Parameters with Proteinuria in Preeclamptic Pregnant Women


ARSLAN M. E., Dinc G.

Archives of Basic and Clinical Research, cilt.7, sa.3, ss.135-141, 2025 (TRDizin) identifier

Özet

Objective: To examine the relation between the mother’s renal and uterine artery (UA) Doppler parameters before and during birth in preeclamptic pregnant women and the degree of proteinuria. Methods: In our study, 30 preeclamptic patients diagnosed in our hospital and 30 healthy pregnant women with matched gestational weeks were evaluated. To determine the amount of protein in the urine, 24-hour urine samples were taken from each patient. Doppler examinations of the UA and renal artery (RA) of the mother were carried out. On the seventh postnatal day, the cases were called in for follow-up, and the uterine and RA Doppler parameters were reevaluated. Spearman correlation analysis was used to assess the association between maternal uterine and RA pulsatility index (PI), resistive index (RI) values, and proteinuria. Results: The preeclampsia group’s antenatal right UA artery PI (1.29 ± 0.5) and RI (0.62 ± 0.13) values were observed to be considerably higher than those of the control group, with PI values (1.01 ± 0.43) and RI values (0.54 ± 0.16). Postnatal right UA PI (1.33 ± 0.56) in preeclampsia group was statistically different compared with postnatal UA PI (1.07 ± 0.32) in control group ( P < 0.05). Postnatal RA PI and RI values were similar in both groups. In preeclamptic patients, right RA PI (1.03 ± 0.29) was statistically higher compared with postnatal RA PI (0.92 ± 0.18). While a significant correlation was found between right UA Doppler parameters and the amount of proteinuria, no correlation was found between RA Doppler parameters and it. Conclusion: The degree of proteinuria and maternal UA Doppler parameters are significantly correlated. There was no correlation between RA Doppler parameters and the amount of proteinuria.