GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME


Turan B., Akinci M. A. , ESİN İ. S. , Dursun O. B.

JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, vol.82, no.3, pp.162-163, 2019 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 82 Issue: 3
  • Publication Date: 2019
  • Doi Number: 10.26650/iuitfd.2019.0011
  • Title of Journal : JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
  • Page Numbers: pp.162-163

Abstract

Triple X syndrome (47, XXX) is a numerical chromosomal alteration that affects 1/1.000 females, in which the individual is born with an extra X chromosome. Trisomy X is a relatively common but under-recognized chromosomal disorder associated with characteristic cognitive and behavioural features of varying severity. We report a 16-year old patient with Triple X syndrome and resistant schizophrenia. It is remarkable that genetic syndromes may be associated with resistance to treatment of psychiatric problems. Therefore in cases with treatment resistance, the genetic analysis should absolutely be examined.