Does anti-oxidant prophylaxis with melatonin prevent adverse outcomes related to increased oxidative stress caused by laparoscopy in experimental rat model?


Cay A., Imamoglu M., Unsal M. A., Aydin S., Alver A., Akyol A., ...More

JOURNAL OF SURGICAL RESEARCH, vol.135, no.1, pp.2-8, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 135 Issue: 1
  • Publication Date: 2006
  • Doi Number: 10.1016/j.jss.2005.12.025
  • Journal Name: JOURNAL OF SURGICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2-8
  • Karadeniz Technical University Affiliated: Yes

Abstract

Background. We hypothesized that prophylaxis with an anti-oxidant should prevent potential adverse outcomes of laparoscopy related to increased oxidative stress in splanchnic organs, including small intestine, liver, and kidneys, and melatonin is the most appropriate agent for this purpose.