Interleukin-6 and interleukin-17 gene polymorphism association with celiac disease in children

Creative Commons License

Akbulut U. E., ÇEBİ A. H., Sag E., IKBAL M., ÇAKIR M.

TURKISH JOURNAL OF GASTROENTEROLOGY, vol.28, no.6, pp.471-475, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 6
  • Publication Date: 2017
  • Doi Number: 10.5152/tjg.2017.17092
  • Journal Name: TURKISH JOURNAL OF GASTROENTEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.471-475
  • Keywords: Celiac disease, Interleukin-6, Interleukin-17, single nucleotide polymorphism, PROMOTER POLYMORPHISMS, SUSCEPTIBILITY, METAANALYSIS, IMMUNITY, RECEPTOR, CELLS
  • Karadeniz Technical University Affiliated: Yes

Abstract

Background/Aims: This study aimed to investigate polymorphisms in the genes responsible for encoding cytokines interleukin-6 (IL-6) (-572G/C) (rs1800796) and IL-17 (-197A/G) (rs2275913) in patients with celiac disease (CD). We further aimed to investigate the relationship between CD symptoms and histopathological findings and the relationship between these polymorphisms.