Interleukin-6 and interleukin-17 gene polymorphism association with celiac disease in children

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Akbulut U. E., ÇEBİ A. H., Sag E., IKBAL M., ÇAKIR M.

TURKISH JOURNAL OF GASTROENTEROLOGY, cilt.28, sa.6, ss.471-475, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 6
  • Basım Tarihi: 2017
  • Doi Numarası: 10.5152/tjg.2017.17092
  • Dergi Adı: TURKISH JOURNAL OF GASTROENTEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.471-475
  • Anahtar Kelimeler: Celiac disease, Interleukin-6, Interleukin-17, single nucleotide polymorphism, PROMOTER POLYMORPHISMS, SUSCEPTIBILITY, METAANALYSIS, IMMUNITY, RECEPTOR, CELLS
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Background/Aims: This study aimed to investigate polymorphisms in the genes responsible for encoding cytokines interleukin-6 (IL-6) (-572G/C) (rs1800796) and IL-17 (-197A/G) (rs2275913) in patients with celiac disease (CD). We further aimed to investigate the relationship between CD symptoms and histopathological findings and the relationship between these polymorphisms.