21st ESPD Annual Meeting, Munich, Almanya, 20 - 22 Mayıs 2022, ss.1-2
Objectives: We aimed to reveal the skin, mucous membrane, hair and nail findings of children who meet the multisystem inflammatory syndrome in children (MIS-C) criteria.
Method: A prospective
case series consisting of 43 children who applied to Karadeniz Technical
University Faculty of Medicine Farabi Hospital between January 2020 and January
2022 and met the criteria for MIS-C according to the diagnostic criteria of the
Centers for Disease Control and Prevention was conducted.
Results:
Of 43 patients diagnosed with MIS-C, 18 (%41,9) were female and 25 (%58,1) were
male. The mean age of the patients is 7.63, the age range is between 7 months
and 15 years. The
results of polymerase chain reaction tests for SARS-CoV-2 were positive for 4 (%9,3)
patients, and the results of SARS-CoV-2 immunoglobulin G tests were positive
for 39 (%90,7) patients. No mucocutaneous
involvement was observed in 3 (%6,9) of the patients. Nonpurulent
conjunctivitis was observed in 25 (%58,1) patients, and periorbital edema was
observed in 4 (%9,3) patients. 4 (%9,3) patients had symmetrical edema of the
hands and feet, and 2 (%4,6) patients had periungual desquamation. While no
oral mucosal findings were observed in 15 (%34,9) patients; 12 (%27,9) patients
had fissured lips, 10 (%23,3) had cheilitis, 8 (%18,6) had diffuse hyperemia of
the oral mucosa, 6 (%13,9) had strawberry tongue, and 3 (%6,9) had herpes
labialis. 21 (%48,8) of the patients had urticarial, 12 (%27,9) of them
maculopapular, 5 (%11,6) patients
livedoid and 1 (%2,3) patient had a skin rash compatible with pseudopernio. No
hair or nail changes were observed in the patients while they were
hospitalized.
Discussion:
In this case series of hospitalized children with definitive MIS-C during the
COVID-19 pandemic, a wide spectrum of mucocutaneous findings was identified.