Acute bronchiolitis is the most common cause of hospitalization among infants. Although antibiotics are not recommended in the absence of secondary bacterial infection, rates of antibiotic usage is high rate in clinical practicesTo test the hypothesis that clarithromycin use in infants with acute viral bronchiolitis shortens  length  of  hospital  stay.One  hundred  sixty-seven  patients  aged  1-24  months  hospitalized  for  treatment with a diagnosis of acute viral bronchiolitis at pediatric clinic between April 2017 and May 2018 were  investigated  retrospectively.  The  patients  were  divided  into  two  separate  groups,  Group  A  (122 

patients), using clarithromycin therapy during hospitalization, and Group B (45 patients), which did not receive clarithromycin (Group B). Demographic and clinical data, treatments received, and duration of hospital stay were obtained from patients’ records.The rate of clarithromycin use in this study was 73%. No statistically significant difference in length of hospital stay was determined between patients receiving

clarithromycin and those receiving no antibiotic therapy. However, length of hospital stay decreased with age. Clarithromycin use elicited no statistically significant decrease in hospital stay in patients with acute viral bronchiolitis.The routine use of clarithromycin is not recommended in acute viral bronchiolitis in the light of its cost and side-effects, and the fact is has no impact on clinical status and hospital stay.