Leiomyoma is the most frequently seen benign tumor of the esophagus. In this article, we report a 41-year-old male patient with complaint of dysphagia. On computed tomography of the thorax, an image resembling a conglomerated lymph node measuring 3.5x2 cm was detected in the lower left paratracheal region. In the esophagoscopy, a submucosally localized mass was seen at 22nd-24th cm of the esophagus. The patient was taken under operation using a thoracoscopic technique and the mass was totally resected through enucleation. Esophageal leiomyoma may mimic mediastinal lymphadenopathy radiologically. For a minimally invasive procedure, thoracoscopic enucleation of these tumors should be the first applied method in surgical treatment.