A rare case of antileucine-rich glioma-inactivated 1 encephalitis in a 14-year-old girl

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Özçifçi G., KAMAŞAK T., Keskin D. B.

Turkish Journal of Pediatrics, cilt.64, sa.3, ss.566-570, 2022 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 64 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.24953/turkjped.2021.1066
  • Dergi Adı: Turkish Journal of Pediatrics
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.566-570
  • Anahtar Kelimeler: leucine-rich glioma-inactivated 1 encephalitis, pediatric, faciobrachial dystonic seizure, autoimmune encephalitis, FACIOBRACHIAL DYSTONIC SEIZURES, COGNITIVE IMPAIRMENT, LIMBIC ENCEPHALITIS, LGI1, FEATURES
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

© 2022, Turkish National Pediatric Society. All rights reserved.Background. Autoimmune limbic encephalitis in children occurs most frequently in those with antibodies against the N-methyl-D-aspartate glutamatergic receptor. We report the case of a 14-year-old girl who was diagnosed with antileucine-rich glioma-inactivated protein 1 limbic encephalitis. Case. A fourteen years old, previously healthy girl applied to the emergency department with suspicion of dystonic seizure, ataxia, gait disturbance and speech disorders. Serum sample of the patient was positive for leucine-rich glioma inactivated protein 1 IgG. Conclusions. Although it is a rare disease in childhood, in the presence of new onset psychotic symptoms or altered mental state, concomittant hyponatremia and unique type of seizures, anti leucine-rich glioma inactivated protein 1encephalitis should be considered in differential diagnosis.