High levels of endothelial progenitor cells and circulating endothelial cells in patients with Behcet's disease and their relationship to disease activity


ARICA D. A. , akşan B., ÖREM A. , ALTINKAYNAK B. A. , YAYLI S. , SÖNMEZ M.

ANAIS BRASILEIROS DE DERMATOLOGIA, vol.94, no.3, pp.320-326, 2019 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 94 Issue: 3
  • Publication Date: 2019
  • Doi Number: 10.1590/abd1806-4841.20198169
  • Title of Journal : ANAIS BRASILEIROS DE DERMATOLOGIA
  • Page Numbers: pp.320-326
  • Keywords: Behcet's disease, Endothelial cells, Matrix Metalloproteinase-9, Vascular endothelial growth factor A, LUPUS-ERYTHEMATOSUS PATIENTS, GROWTH-FACTOR, SERUM-LEVELS, GENE POLYMORPHISMS, PERIPHERAL-BLOOD, MATRIX-METALLOPROTEINASE-9, ASSOCIATION, MMP-9, NEOVASCULARIZATION, MOBILIZATION

Abstract

BACKGROUND: Behcet's disease is a multisystemic vasculitis, associated with vascular endothelial dysfunction. Currently, the prognosis is unpredictable, because there is still no valid laboratory marker indicating the disease activity in Behcet's disease. Endothelial progenitor cells and circulating endothelial cells are newly introduced hematological markers which are presumed to take part in the pathogenesis of vasculitis.