The main purpose of this study is to examine the effects of configurations of structural walls on the seismic behavior of multi-storey RC buildings. For this purpose, four different structural systems for buildings are considered. One of them is a frame system and the others are three different structural walls systems. Totally, four different buildings having 6, 10 and 12 stories are considered for analysis. The SAP2000 structural analysis program is used for analysis and the IDS-99 package program is used for determination of cross sections of columns, beams, slabs and structural walls. Finally, shear forces, bending moments and displacements obtained by seismic analysis for selected three columns in four different buildings, also forces and bending moments obtained for structural walls in three different structural wall systems are compared.