Synthesis and Biological Evaluation of New Tricyclic Dihydropyridine Based Derivatives on Potassium Channels
IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, vol.15, no.4, pp.763-775, 2016 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 15 Issue: 4
- Publication Date: 2016
- Journal Name: IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.763-775
- Karadeniz Technical University Affiliated: No
Abstract
The present study reports a microwave-assisted method for the synthesis of twelve novel tricyclic 1,4-dihydropyridine derivatives in which dimethyl-substituted cyclohexane and / or tetrahydrothiophene rings are fused to the DHP ring. The structures of the compounds were confirmed by spectral methods and elemental analysis.