Synthesis, acetylcholinesterase, butyrylcholinesterase and tyrosinase inhibition, and antioxidant studies of 2-[2-(substituted-benzyl)-4(7)-phenyl-1H-benzimidazol-1-yl] acetohydrazides and methyl 2-[2-(substituted-benzyl)-4(7)-phenyl-1H-benzimidazol-1-yl] acetates


Gumus M. K. , DOĞAN İ. S. , Barut B., ÖZEL A., KAHVECİ B.

BULGARIAN CHEMICAL COMMUNICATIONS, vol.49, pp.107-114, 2017 (Peer-Reviewed Journal) identifier

  • Publication Type: Article / Article
  • Volume: 49
  • Publication Date: 2017
  • Journal Name: BULGARIAN CHEMICAL COMMUNICATIONS
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.107-114

Abstract

In this research study we intend to synthesize six new 2-[2-(substituted-benzyl)-4(7)-phenyl-1H-benzimidazol-1-yl] acetohydrazides (8a-f) and six new methyl 2-[2-(substituted-benzyl)-4(7)-phenyl-1H-benzimidazol-1-yl] acetates (7a-f) with potency inhibiting acetylcholinesterase, butyrylcholinesterase and tyrosinase enzymes and antioxidant activities.