Synthesis, acetylcholinesterase, butyrylcholinesterase and tyrosinase inhibition, and antioxidant studies of 2-[2-(substituted-benzyl)-4(7)-phenyl-1H-benzimidazol-1-yl] acetohydrazides and methyl 2-[2-(substituted-benzyl)-4(7)-phenyl-1H-benzimidazol-1-yl] acetates

Gumus, M.; DOĞAN, İNCİ; Barut, BURAK; ÖZEL, ARZU; KAHVECİ, BAHİTTİN

Synthesis, acetylcholinesterase, butyrylcholinesterase and tyrosinase inhibition, and antioxidant studies of 2-[2-(substituted-benzyl)-4(7)-phenyl-1H-benzimidazol-1-yl] acetohydrazides and methyl 2-[2-(substituted-benzyl)-4(7)-phenyl-1H-benzimidazol-1-yl] acetates

Gumus M. K., DOĞAN İ. S., Barut B., ÖZEL A., KAHVECİ B.

BULGARIAN CHEMICAL COMMUNICATIONS, cilt.49, ss.107-114, 2017 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 49
Basım Tarihi: 2017
Dergi Adı: BULGARIAN CHEMICAL COMMUNICATIONS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.107-114
Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

In this research study we intend to synthesize six new 2-[2-(substituted-benzyl)-4(7)-phenyl-1H-benzimidazol-1-yl] acetohydrazides (8a-f) and six new methyl 2-[2-(substituted-benzyl)-4(7)-phenyl-1H-benzimidazol-1-yl] acetates (7a-f) with potency inhibiting acetylcholinesterase, butyrylcholinesterase and tyrosinase enzymes and antioxidant activities.