Plasma activity of of thrombin activatable fibrinolysis inhibitor in Crimean-Congo hemorrhagic fever


Sonmez M. , AYDIN K., DURMUS A., SUCU N., Yilmaz M. , AKDOGAN E., ...Daha Fazla

JOURNAL OF INFECTION, cilt.55, ss.184-187, 2007 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 55 Konu: 2
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.jinf.2007.02.010
  • Dergi Adı: JOURNAL OF INFECTION
  • Sayfa Sayıları: ss.184-187

Özet

Objectives: Crimean-Congo hemorrhagic fever (CCHF) is a potentially fatal viral infection. The exact mechanism for hemorrhage remains unknown. Thrombin activatable fibrinolysis inhibitor (TAFI) is a plasma procarboxypeptidase B-like proenzyme and synthesized in the liver, down-regulating fibrinolysis. In this study, we measured the TAR activity in plasma of patients with CCHF to examine the relationship between hemorrhage and the pathogenesis of CCHF.