Subacute sclerosing panencephalltis (SSPE)

Sahin S., Uysal S.

TURK PEDIATRI ARSIVI-TURKISH ARCHIVES OF PEDIATRICS, cilt.43, sa.3, ss.72-79, 2008 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 3
  • Basım Tarihi: 2008
  • Dergi Adı: TURK PEDIATRI ARSIVI-TURKISH ARCHIVES OF PEDIATRICS
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.72-79
  • Anahtar Kelimeler: Child, measles, subacute sclerosing panencephalitis
  • Karadeniz Teknik Üniversitesi Adresli: Hayır

Özet

Subacute sclerosing panencephalitis (SSPE) is a neurodegenerative disease with a poor prognosis. It is characterized by the persistent infection of the brain by the measles virus. Mechanisms causing persistence and reactivation of measles virus in SSPE are unknown. Patients usually have behavioral changes, myoclonus, dementia, visual disturbances, and pyramidal and extrapyramidal signs. No treatment has a proven role. A decline in frequency has been noticed in most of the developed countries, whereas it continues to be high in developing countries. Effective immunization against measles is the only solution presently available to the problem of this dreaded disease. We aimed to give an overall review on SSPE in this paper.