This study examines the trade and use of medical and aromatic herbs within 24 different provinces of Turkey. Face-to-face interviews were conducted with 214 herbalists and 933 customers, which were then used to develop demographic profiles. The most commonly sold herbs were Mentha pulegium, Tilia tomentosa, Zingiber officinale, Salvia spp. and Ceratonia siliqua. The dataset included 2297 records on purchase quantities and usage, which showed that the main uses were foodspice, and digestive, respiratory system, dermatological, and neurological disorders. The most commonly used parts of the herbs are leaves, flowers and fruits. The preferred means of administration are infusion, powder and decoction.