Flow cytometry tear analysis in patients with chronic allergic conjunctivitis

Avunduk A., Avunduk M., Dayioglu Y., Centinkaya K.

JAPANESE JOURNAL OF OPHTHALMOLOGY, vol.41, no.2, pp.67-70, 1997 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 2
  • Publication Date: 1997
  • Doi Number: 10.1016/s0021-5155(97)00012-9
  • Journal Name: JAPANESE JOURNAL OF OPHTHALMOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.67-70
  • Karadeniz Technical University Affiliated: No

Abstract

Tears from patients with chronic allergic conjunctivitis were analyzed with flow cytometry to determine the function of the T lymphocyte-related immunological reactions in the disease pathogenesis. Twenty-eight patients and 22 normal volunteers were studied; tears were obtained with capillary tubes. T helper/T suppressor ratios and the percentages of HLA DR+, CD23+, and CD3+ cells were significantly higher in patients than in controls. This study provides support for the hypothesis that chronic allergic conjunctivitis results from T lymphocyte-related immunological reactions. (C) 1997 Japanese Ophthalmological Society.