Flow cytometry tear analysis in patients with chronic allergic conjunctivitis

Avunduk A., Avunduk M., Dayioglu Y., Centinkaya K.

JAPANESE JOURNAL OF OPHTHALMOLOGY, cilt.41, sa.2, ss.67-70, 1997 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 41 Konu: 2
  • Basım Tarihi: 1997
  • Doi Numarası: 10.1016/s0021-5155(97)00012-9
  • Sayfa Sayıları: ss.67-70


Tears from patients with chronic allergic conjunctivitis were analyzed with flow cytometry to determine the function of the T lymphocyte-related immunological reactions in the disease pathogenesis. Twenty-eight patients and 22 normal volunteers were studied; tears were obtained with capillary tubes. T helper/T suppressor ratios and the percentages of HLA DR+, CD23+, and CD3+ cells were significantly higher in patients than in controls. This study provides support for the hypothesis that chronic allergic conjunctivitis results from T lymphocyte-related immunological reactions. (C) 1997 Japanese Ophthalmological Society.