Karbonmonoksit intoksikasyonundan organ donasyonuna; ağır pulmoner hasarda organ koruyucu mekanik ventilasyon


PEHLİVANLAR KÜÇÜK M., KÖYLÜ İLKAYA N., ÖZTÜRK Ç. E. , CEBECİ H., AYDIN D., ÜLGER F.

Tuberk Toraks, vol.66, no.3, pp.253-257, 2018 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Case Report
  • Volume: 66 Issue: 3
  • Publication Date: 2018
  • Doi Number: 10.5578/tt.67100
  • Journal Name: Tuberk Toraks
  • Journal Indexes: Emerging Sources Citation Index, Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.253-257
  • Keywords: APRV, brain death, carbonmonoxide intoxication, organ donation, PRESSURE RELEASE VENTILATION, CARDIAC TRANSPLANTATION, POISONED DONORS, ALLOGRAFTS

Abstract

Organ donation is a matter of concern in critically ill patients who need intensive care after carbon-monoxide (CO) intoxication. A 26-year-old female patient was unconscious after having spent 20 minutes in the bathroom with a water heater (70% butane and 30% propane mixture). In the CT of the patient with Glasgow Coma Scale (GCS) 3, ventricular system was erased, white-gray matter separation was lost and fissures were observed as erased. Torax CT showed conspicuous areas showing air bronchograms in both lung bases and posterior areas and diffuse frosted glass densities in other areas. In a patient with no improvement in consciousness; apnea test, neurological examination and CT angiography showed that there was no blood flow in the brain and brain death was confirmed. On the second day of hospitalization, the relatives gave their approval for the donation. It may also be advantageous to use oxygen at high concentrations in carbonmonoxide poisoning as it may allow recruitment of closed alveoli. Successful kidney, heart, lung, liver and pancreas transplants from donors exposed to CO have been reported. Carbonmonoxide intoxication may be appropriate for transplantation for patients who are waiting for organs of brain death cases where the organ preservation is well done. Although carbonmonoxide intoxication has failed in the literature, it shows that there is no definite contraindication.