Necrotizing enterocolitis increases the bone resorption in premature infants

Cakir M., Mungan I., Karahan C., Can G., Okten A. N.

EARLY HUMAN DEVELOPMENT, vol.82, no.6, pp.405-409, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 82 Issue: 6
  • Publication Date: 2006
  • Doi Number: 10.1016/j.earlhumdev.2005.10.015
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.405-409
  • Keywords: bone turnover, necrotizing enterocolitis, premature infants, glucagon like peptide-2, GLUCAGON-LIKE PEPTIDE-2, BIRTH-WEIGHT INFANTS, SHORT-BOWEL PATIENTS, GASTROINTESTINAL-DISEASE, NO COLON, GROWTH, EXCRETION, TURNOVER, COLLAGEN, TERM
  • Karadeniz Technical University Affiliated: Yes


Background: Necrotizing enterocolitis is a common neonatal gastrointestinal disease that affects approximately 10% of premature infants less than 1500 g. The average mortality is 20-40% and survivors may present with diarrhea or malabsorption, intestinal strictures and fistulas, feeding abnormalities and failure to thrive. It is not clear whether the higher incidence of this gastrointestinal disease in premature infants contributes to the risk of osteopenia of prematurity.