Pregnancy outcome after TNF-alpha inhibitor therapy during the first trimester: a prospective multicentre cohort study


Weber-Schoendorfer C., Oppermann M., Wacker E., Bernard N., Beghin D., Cuppers-Maarschalkerweerd B., ...Daha Fazla

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, cilt.80, ss.727-739, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 80 Konu: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1111/bcp.12642
  • Dergi Adı: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
  • Sayfa Sayıları: ss.727-739

Özet

AimsTNF- inhibitors are considered relatively safe in pregnancy but experience is still limited. The aim of this study was to evaluate the risk of major birth defects, spontaneous abortion, preterm birth and reduced birth weight after first trimester exposure to TNF- inhibitors.