Microvascular Invasion in Hepatocellular Carcinoma and Liver Transplant

Jakhete N., Saberi B., Jonassaint N. L., Cosar A. M., Luu H., Kim A., ...More

EXPERIMENTAL AND CLINICAL TRANSPLANTATION, vol.14, pp.14-18, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 14
  • Publication Date: 2016
  • Doi Number: 10.6002/ect.tondtdtd2016.l17
  • Journal Name: EXPERIMENTAL AND CLINICAL TRANSPLANTATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.14-18
  • Keywords: Alpha-fetoprotein, Hepatitis C, Liver cancer, Milan Criteria, ALPHA-FETOPROTEIN, TUMOR RECURRENCE, EXPERIENCE, PREDICTORS, RESECTION, SIZE
  • Karadeniz Technical University Affiliated: Yes

Abstract

Objectives: Curative therapy for hepatocellular carcinoma is liver transplant. To date, the Milan Criteria remain the best pretransplant clinical surrogate for tumor behavior and overall prognosis. Microvascular invasion portends a poor prognosis; however, it is often undetectable before transplant. Furthermore, its pretransplant indicators are not well established. In this study, we investigated the presurgical and pathologic predictors of microvascular invasion in patients with hepatocellular carcinoma.