Long-term disability trajectories in primary progressive MS patients: A latent class growth analysis


Signori A., Izquierdo G., Lugaresi A., Hupperts R., Grand'Maison F., Sola P., ...More

MULTIPLE SCLEROSIS JOURNAL, vol.24, no.5, pp.642-652, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 5
  • Publication Date: 2018
  • Doi Number: 10.1177/1352458517703800
  • Journal Name: MULTIPLE SCLEROSIS JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.642-652
  • Keywords: Primary progressive multiple sclerosis, disability, long-term, trajectories, clinical trials, heterogeneity, MULTIPLE-SCLEROSIS, NATURAL-HISTORY, DOUBLE-BLIND, MULTICENTER, PHASE
  • Karadeniz Technical University Affiliated: Yes

Abstract

Background: Several natural history studies on primary progressive multiple sclerosis (PPMS) patients detected a consistent heterogeneity in the rate of disability accumulation.