Investigation of the effect of trazodone on spontaneous and acetylcholine-induced bladder detrusor smooth muscle contractions

Burunsuz Ö., Özdengül F., Gıca Ş., Şen A., Şahin Z.

DUSUNEN ADAM-JOURNAL OF PSYCHIATRY AND NEUROLOGICAL SCIENCES, cilt.35, sa.1, ss.43-47, 2022 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 1
  • Basım Tarihi: 2022
  • Doi Numarası: 10.14744/dajpns.2022.00170
  • Dergi Adı: DUSUNEN ADAM-JOURNAL OF PSYCHIATRY AND NEUROLOGICAL SCIENCES
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, EMBASE, Psycinfo, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.43-47
  • Anahtar Kelimeler: Antidepressant, bladder, detrusor, smooth muscle contraction, trazodone, UNITED-STATES EXPERIENCE, PIG URINARY-BLADDER, RECEPTOR SUBTYPES, ANTIDEPRESSANTS, STIMULATION, ATROPINE
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Objective: The management of psychiatric patients is often complicated by medical comorbidities, complex pharmacological regimens, and side effects secondary to these regimens. In the current study, it was aimed to investigate the effects and mechanism of action of trazodone on rat bladder smooth muscle contractility in vitro.