KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI, cilt.13, sa.1, ss.103-108, 2007 (SCI-Expanded)
The main goal of BVDV vaccination is to induce adequate immunity in dams for protecting the infection of foetuses against both genotypes of BVDV-1 and BVDV-2 viruses during pregnancy and thus preventing the establishment of persistent infections as well as preventing severe postnatal infections caused by BVDV-2. The most important problem for BVDV vaccine development is the existence of diversity of BVDV isolates in worldwide. So far, a few BVDV vaccines and vaccination strategies have been given good results for preventing transplacental infections. Live-attenuated BVDV vaccines are better for protection but they have safety concerns. Inactivated vaccines are questionable for inducing adequate broad immune response. There is still a necessity for the development of a better and a novel vaccine for the control of BVDV infections.