Synthesis of Novel 3-(4-tert-Butylphenyl)-5-Cylopropyl-4H-1,2,4-Triazole Derivatives with Antioxidative and Antimicrobial Activities

YILDIRIM N.

LETTERS IN DRUG DESIGN & DISCOVERY, vol.17, no.8, pp.954-964, 2020 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 8
  • Publication Date: 2020
  • Doi Number: 10.2174/1570180817999200424073524
  • Journal Name: LETTERS IN DRUG DESIGN & DISCOVERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, Biotechnology Research Abstracts, EMBASE
  • Page Numbers: pp.954-964
  • Keywords: 4H-1,2,4-triazoles, 4-arylmethyleneamino-4H-1,2,4-triazoles, Reactive oxygen species, phthalonitrile derivates, antioxidant, antimicrobial, SCHIFF-BASES, BIOLOGICAL EVALUATION, 1,2,4-TRIAZOLE DERIVATIVES, TRIAZOLE, ANTICANCER, INHIBITORS, AGENTS, DESIGN, ANTIBACTERIAL, FUNGICIDES
  • Karadeniz Technical University Affiliated: Yes

Abstract

Background: In this work, new heterocyclic compounds containing 3-(4-tert-butylphenyl)-5-cyclopropyl- 4H-1,2,4-triazole ring were synthesized, starting from iminoester hydrochlorides and 4-tert-butylbenzhyrazide.