Advances in the naturalα‐glucosidase inhibitors

Şöhretoğlu D., Renda G., Arroo R., Xiao J., Sarı S.

e-FOOD, vol.4, no.112, pp.1-19, 2023 (Scopus)

  • Publication Type: Article / Review
  • Volume: 4 Issue: 112
  • Publication Date: 2023
  • Doi Number: 10.1002/efd2.112
  • Journal Name: e-FOOD
  • Journal Indexes: Scopus, CAB Abstracts, Directory of Open Access Journals
  • Page Numbers: pp.1-19
  • Karadeniz Technical University Affiliated: Yes

Abstract

α‐Glucosidase (AG) inhibitors, one of the classes of oral antidiabetics used totreat type 2 diabetes mellitus, delay digestion and absorption of glucose, which inturn, has a lowering effect on postprandial blood glucose and insulin levels.Natural products are a great source for the development of new AG inhibitorydrug candidates. We aim to summarize advances in natural AG inhibitorsaccording to their secondary metabolite groups in the last decade. Theirmechanisms of action and structure–activity relationships will especially bediscussed.